Anti-Phospho-TPH1-Ser260 antibody (STJA0003814)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser260 conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Tryptophan Hydroxylase-Ser260 for use in WB in Human, Rat, Bovine, Canine, Chicken, Mouse and Zebrafish samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Bovine/Canine/Chicken/Mouse/Zebrafish |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:1000 |
| Formulation | 100 ยตl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 ยตg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Tph1 |
| Gene ID | 24848 |
| Uniprot ID | TPH1_RAT |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser260 conjugated to KLH. |
Additional Info
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome. |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
| Protein Name | Tryptophan 5-Hydroxylase 1Tryptophan 5-Monooxygenase 1 |
| Database Links | Reactome: R-RNO-209931 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Tryptophan 5-Hydroxylase 1 antibodyAnti-Tryptophan 5-Monooxygenase 1 antibodyAnti-Tph1 antibodyAnti-Tph antibody |
Information sourced from Uniprot.org