| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Rat/Bovine/Canine/Chicken/Mouse/Zebrafish |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Phospho-Tryptophan Hydroxylase-Ser260 is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Purification: | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range: | WB 1:1000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | Tph1 |
| Gene ID: | 24848 |
| Uniprot ID: | TPH1_RAT |
| Immunogen: | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser260 conjugated to KLH. |
| Post Translational Modifications | Ubiquitinated, leading to its degradation by the proteasome. Ubiquitinated is triggered by phosphorylation. Phosphorylated.triggering degradation by the proteasome. |
| Function | Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. |
| Protein Name | Tryptophan 5-Hydroxylase 1 Tryptophan 5-Monooxygenase 1 |
| Database Links | Reactome: R-RNO-209931 |
| Alternative Antibody Names | Anti-Tryptophan 5-Hydroxylase 1 antibody Anti-Tryptophan 5-Monooxygenase 1 antibody Anti-Tph1 antibody Anti-Tph antibody |
Information sourced from Uniprot.org