• Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using Stathmin 1 (Phospho-Ser24) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from Jurkat cells treated with PMA 1ng/ml 15', using Stathmin 1 (Phospho-Ser24) Antibody. The lane on the right is blocked with the phospho peptide.
  • Western blot analysis of various cells using Phospho-Op18 (S25) Polyclonal Antibody

Anti-Phospho-STMN1-Ser25 antibody (9-58 aa) (STJ90358)

SKU:
STJ90358

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Stathmin-Ser25 (9-58 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:10000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: STMN1
Gene ID: 3925
Uniprot ID: STMN1_HUMAN
Immunogen Region: 9-58 aa
Specificity: Phospho-Op18 (S25) Polyclonal Antibody detects endogenous levels of Op18 protein only when phosphorylated at S25.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Stathmin 1 around the phosphorylation site of Ser24 at the amino acid range 9-58
Post Translational Modifications Many different phosphorylated forms are observed depending on specific combinations among the sites which can be phosphorylated. MAPK is responsible for the phosphorylation of stathmin in response to NGF. Phosphorylation at Ser-16 seems to be required for neuron polarization. Phosphorylation at Ser-63 reduces tubulin binding 10-fold and suppresses the MT polymerization inhibition activity.
Function Involved in the regulation of the microtubule (MT) filament system by destabilizing microtubules. Prevents assembly and promotes disassembly of microtubules. Phosphorylation at Ser-16 may be required for axon formation during neurogenesis. Involved in the control of the learned and innate fear.
Protein Name Stathmin
Leukemia-Associated Phosphoprotein P18
Metablastin
Oncoprotein 18
Op18
Phosphoprotein P19
Pp19
Prosolin
Protein Pr22
Pp17
Database Links Reactome: R-HSA-1251985
Cellular Localisation Cytoplasm
Cytoskeleton
Alternative Antibody Names Anti-Stathmin antibody
Anti-Leukemia-Associated Phosphoprotein P18 antibody
Anti-Metablastin antibody
Anti-Oncoprotein 18 antibody
Anti-Op18 antibody
Anti-Phosphoprotein P19 antibody
Anti-Pp19 antibody
Anti-Prosolin antibody
Anti-Protein Pr22 antibody
Anti-Pp17 antibody
Anti-STMN1 antibody
Anti-C1orf215 antibody
Anti-LAP18 antibody
Anti-OP18 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance