| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-Phospho-Signal transducer and activator of transcription 5A-Ser725/730 is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | STAT5A |
| Gene ID: | 6776 |
| Uniprot ID: | STA5A_HUMAN |
| Specificity: | This antibody detects endogenous levels of STAT5A/B (Phospho-Ser725/730) at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human STAT5A/B (Phospho-Ser725/730) |
| Function | Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Mediates cellular responses to ERBB4. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the GAS element and activates PRL-induced transcription. Regulates the expression of milk proteins during lactation. |
| Protein Name | Signal Transducer And Activator Of Transcription 5a |
| Database Links | Reactome: R-HSA-1170546Reactome: R-HSA-1251985Reactome: R-HSA-1266695Reactome: R-HSA-1433557Reactome: R-HSA-1839117Reactome: R-HSA-186763Reactome: R-HSA-2586552Reactome: R-HSA-512988Reactome: R-HSA-8854691Reactome: R-HSA-8983432Reactome: R-HSA-8985947Reactome: R-HSA-9020558Reactome: R-HSA-9020958Reactome: R-HSA-9027283Reactome: R-HSA-9645135Reactome: R-HSA-9670439Reactome: R-HSA-9674555Reactome: R-HSA-9702518Reactome: R-HSA-9703465Reactome: R-HSA-9705462Reactome: R-HSA-9725371Reactome: R-HSA-982772 |
| Cellular Localisation | CytoplasmNucleusTranslocated Into The Nucleus In Response To Phosphorylation |
| Alternative Antibody Names | Anti-Signal Transducer And Activator Of Transcription 5a antibodyAnti-STAT5A antibodyAnti-STAT5 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
