Anti-Phospho-S6K2-Ser371 antibody [R01-4A5] (STJA0033928)

SKU:
STJA0033928
£133.50 - £281.50
Processing The item has been added

Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Phospho-S6K2-Ser371 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R01-4A5
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: RPS6KB2
Gene ID: 6199
Uniprot ID: KS6B2_HUMAN
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser371 of human P70 S6 Kinase beta
Post Translational Modifications Phosphorylated and activated by MTOR. Phosphorylation by PKC within the NLS in response to mitogenic stimuli causes cytoplasmic retention.
Function Phosphorylates specifically ribosomal protein S6. Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7.
Protein Name Ribosomal Protein S6 Kinase Beta-2
S6k-Beta-2
S6k2
70 Kda Ribosomal Protein S6 Kinase 2
P70s6k2
P70-S6k 2
S6 Kinase-Related Kinase
Srk
Serine/Threonine-Protein Kinase 14b
P70 Ribosomal S6 Kinase Beta
S6k-Beta
P70 S6 Kinase Beta
P70 S6k-Beta
P70 S6kb
P70-Beta
Database Links Reactome: R-HSA-198693
Reactome: R-HSA-5674400
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-Ribosomal Protein S6 Kinase Beta-2 antibody
Anti-S6k-Beta-2 antibody
Anti-S6k2 antibody
Anti-70 Kda Ribosomal Protein S6 Kinase 2 antibody
Anti-P70s6k2 antibody
Anti-P70-S6k 2 antibody
Anti-S6 Kinase-Related Kinase antibody
Anti-Srk antibody
Anti-Serine/Threonine-Protein Kinase 14b antibody
Anti-P70 Ribosomal S6 Kinase Beta antibody
Anti-S6k-Beta antibody
Anti-P70 S6 Kinase Beta antibody
Anti-P70 S6k-Beta antibody
Anti-P70 S6kb antibody
Anti-P70-Beta antibody
Anti-RPS6KB2 antibody
Anti-STK14B antibody

Information sourced from Uniprot.org