| Host: | Rabbit |
| Applications: | WB/IHC-P/IP |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit monoclonal anti-Phospho-PTS-Ser19 for use in WB, IHC-P and IP in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Monoclonal |
| Clone ID : | R05-7G8 |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Purification: | Affinity Purified |
| Concentration: | 0.3 mg/mL |
| Dilution Range: | WB 1:500-1:1000IHC 1:50-1:100IP 1:20 |
| Storage Instruction: | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
| Gene Symbol: | PTS |
| Gene ID: | 5805 |
| Uniprot ID: | PTPS_HUMAN |
| Immunogen: | A synthetic phosphopeptide corresponding to residues surrounding Ser19 of human PTS/PTPS |
| Post Translational Modifications | Phosphorylation of Ser-19 is required for maximal enzyme activity. |
| Function | Involved in the biosynthesis of tetrahydrobiopterin, an essential cofactor of aromatic amino acid hydroxylases. Catalyzes the transformation of 7,8-dihydroneopterin triphosphate into 6-pyruvoyl tetrahydropterin. |
| Protein Name | 6-Pyruvoyl Tetrahydrobiopterin SynthasePtp SynthasePtps |
| Database Links | Reactome: R-HSA-1474151 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Pyruvoyl Tetrahydrobiopterin Synthase antibodyAnti-Ptp Synthase antibodyAnti-Ptps antibodyAnti-PTS antibody |
Information sourced from Uniprot.org
