• Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).
  • Western Blot analysis of Hela treated or untreated by LPS lysis, using primary antibody at 1:1000 dilution. Secondary antibody (STJS000791) was diluted at 1:10000

Anti-Phospho-PPARA-Ser21 antibody (STJA0009830)

SKU:
STJA0009830

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Peroxisome proliferator-activated receptor alpha-Ser21 is suitable for use in Western Blot and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-p 1:50-300
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PPARA
Gene ID: 5465
Uniprot ID: PPARA_HUMAN
Specificity: This antibody detects endogenous levels of Human PPAR Alpha (Phospho Ser21)
Immunogen: Synthesized peptide derived from human PPAR Alpha (Phospho Ser21)
Tissue Specificity Skeletal muscle, liver, heart and kidney. Expressed in monocytes.
Function Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Protein Name Peroxisome Proliferator-Activated Receptor Alpha
Ppar-Alpha
Nuclear Receptor Subfamily 1 Group C Member 1
Database Links Reactome: R-HSA-1368082
Reactome: R-HSA-1368108
Reactome: R-HSA-1989781
Reactome: R-HSA-2151201
Reactome: R-HSA-2426168
Reactome: R-HSA-381340
Reactome: R-HSA-383280
Reactome: R-HSA-400206
Reactome: R-HSA-400253
Reactome: R-HSA-4090294
Reactome: R-HSA-9707564
Reactome: R-HSA-9707616
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Peroxisome Proliferator-Activated Receptor Alpha antibody
Anti-Ppar-Alpha antibody
Anti-Nuclear Receptor Subfamily 1 Group C Member 1 antibody
Anti-PPARA antibody
Anti-NR1C1 antibody
Anti-PPAR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance