Anti-Phospho-PFKFB2-Ser483 antibody (451-500 aa) (STJ90871)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PFKFB2 around the phosphorylation site of Ser483 at the amino acid range 451-500
General Information
| Short Description | Rabbit polyclonal anti-Phospho-6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2-Ser483 (451-500 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:40000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PFKFB2 |
| Gene ID | 5208 |
| Uniprot ID | F262_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PFKFB2 around the phosphorylation site of Ser483 at the amino acid range 451-500 |
| Immunogen Region | 451-500 aa |
| Specificity | Phospho-PFK-2 car (S483) Polyclonal Antibody detects endogenous levels of PFK-2 car protein only when phosphorylated at S483. |
Additional Info
| Post Translational Modifications | Phosphorylation by AMPK stimulates activity. |
| Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
| Protein Name | 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 26pf-2-K/Fru-2 -6-P2ase 2Pfk/Fbpase 26pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase |
| Database Links | Reactome: R-HSA-9634600 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase 2 antibodyAnti-Pfk/Fbpase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibodyAnti-PFKFB2 antibody |
Information sourced from Uniprot.org