Anti-Phospho-NMDA Epsilon 1/2-Tyr1246/1252 antibody (1216-1265 aa) (STJ91307)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human NMDAR2A/B around the phosphorylation site of Tyr1246/1252 at the amino acid range 1216-1265
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Glutamate receptor ionotropic, NMDA 2A and Glutamate receptor ionotropic, NMDA 2B-Tyr1246/1252 (1216-1265 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommenda |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | GRIN2AGRIN2B |
| Gene ID | 29032904 |
| Uniprot ID | NMDE1_HUMANNMDE2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human NMDAR2A/B around the phosphorylation site of Tyr1246/1252 at the amino acid range 1216-1265 |
| Immunogen Region | 1216-1265 aa |
| Specificity | Phospho-NMDA Epsilon 1/2 (Y1246/1252) Polyclonal Antibody detects endogenous levels of NMDA Epsilon 1/2 protein only when phosphorylated at Y1246/1252. |
Additional Info
| Protein Name | Glutamate Receptor Ionotropic - Nmda 2aGlun2aGlutamate Nmda Receptor Subunit Epsilon-1N-Methyl D-Aspartate Receptor Subtype 2aNmdar2aNr2aHnr2a |
| Database Links | Reactome: R-HSA-438066Reactome: R-HSA-6794361Reactome: R-HSA-8849932Reactome: R-HSA-9022699Reactome: R-HSA-9609736Reactome: R-HSA-9617324Reactome: R-HSA-9620244 |
| Cellular Localisation | Cell ProjectionDendritic SpineCell MembraneMulti-Pass Membrane ProteinCell JunctionSynapsePostsynaptic Cell MembraneCytoplasmic Vesicle MembraneExpression At The Dendrite Cell Membrane And At Synapses Is Regulated By Sorcs2 And The Retromer Complex |
| Alternative Antibody Names | Anti-Glutamate Receptor Ionotropic - Nmda 2a antibodyAnti-Glun2a antibodyAnti-Glutamate Nmda Receptor Subunit Epsilon-1 antibodyAnti-N-Methyl D-Aspartate Receptor Subtype 2a antibodyAnti-Nmdar2a antibodyAnti-Nr2a antibodyAnti-Hnr2a antibodyAnti-GRIN2A antibodyAnti-NMDAR2A antibody |
Information sourced from Uniprot.org