Host: |
Rabbit |
Applications: |
WB/ICC |
Reactivity: |
Human/Mouse/Rat/Bovine |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Phospho-Myosin Light Chain-Ser-1 is suitable for use in Western Blot and Immunocytochemistry research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS + 1 mg/ml BSA, 0.05% NaN3 and 50% glycerol |
Purification: |
Antigen Affinity Purified |
Dilution Range: |
WB 1:1000IHCICC 1:100IP |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
MYL12A |
Gene ID: |
10627 |
Uniprot ID: |
ML12A_HUMAN |
Specificity: |
The antibody detects a 20 kDa* band corresponding to the molecular weight of myosin light chain in human A431 treated with EGF or calyculin A. In addition, the antibody detects the 20 kDa myosin light chain in mouse C2C12, rat PC12, and rabbit fibrob |
Immunogen: |
Phospho-MLC (Ser-1) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1 in bovine myosin regulatory light chain 9 (Myl9). This peptide sequence is highly conserved in human, rat, and mouse Myl9, and in other smoo |
Function | Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. |
Protein Name | Myosin Regulatory Light Chain 12aEpididymis Secretory Protein Li 24Hel-S-24Mlc-2bMyosin RlcMyosin Regulatory Light Chain 2 - NonsarcomericMyosin Regulatory Light Chain Mrlc3 |
Database Links | Reactome: R-HSA-3928664Reactome: R-HSA-445355 |
Alternative Antibody Names | Anti-Myosin Regulatory Light Chain 12a antibodyAnti-Epididymis Secretory Protein Li 24 antibodyAnti-Hel-S-24 antibodyAnti-Mlc-2b antibodyAnti-Myosin Rlc antibodyAnti-Myosin Regulatory Light Chain 2 - Nonsarcomeric antibodyAnti-Myosin Regulatory Light Chain Mrlc3 antibodyAnti-MYL12A antibodyAnti-MLCB antibodyAnti-MRLC3 antibodyAnti-RLC antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance