• Western blot analysis of lysates from SH-SY5Y cells, primary antibody was diluted at 1:1000, 4°C over night

Anti-Phospho-MCL1-Thr163 antibody (STJ194722)

SKU:
STJ194722

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/ELISA/IHC
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Induced myeloid leukemia cell differentiation protein Mcl-1-Thr163 is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
IHC-P 1:50-300
ELISA 2000-20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MCL1
Gene ID: 4170
Uniprot ID: MCL1_HUMAN
Specificity: This antibody detects endogenous levels of Human Mcl-1 (phospho-Thr163)
Immunogen: Synthesized phosho peptide around human Mcl-1 (Thr163)
Function Involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Mediates its effects by interactions with a number of other regulators of apoptosis. Isoform 1 inhibits apoptosis. Isoform 2 promotes apoptosis.
Protein Name Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1
Bcl-2-Like Protein 3
Bcl2-L-3
Bcl-2-Related Protein Eat/Mcl1
Mcl1/Eat
Database Links Reactome: R-HSA-6785807
Cellular Localisation Membrane
Single-Pass Membrane Protein
Cytoplasm
Mitochondrion
Nucleus
Nucleoplasm
Cytoplasmic
Associated With Mitochondria
Alternative Antibody Names Anti-Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 antibody
Anti-Bcl-2-Like Protein 3 antibody
Anti-Bcl2-L-3 antibody
Anti-Bcl-2-Related Protein Eat/Mcl1 antibody
Anti-Mcl1/Eat antibody
Anti-MCL1 antibody
Anti-BCL2L3 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance