Anti-Phospho-KCNA3-Tyr187 antibody (101-150 aa) (STJ91099)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Kv1.3/KCNA3 around the phosphorylation site of Tyr135 at the amino acid range 101-150
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Potassium voltage-gated channel subfamily A member 3 channel HuKIII-Tyr187 (101-150 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related rea |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | KCNA3 |
| Gene ID | 3738 |
| Uniprot ID | KCNA3_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Kv1.3/KCNA3 around the phosphorylation site of Tyr135 at the amino acid range 101-150 |
| Immunogen Region | 101-150 aa |
| Specificity | Phospho-Kv1.3 (Y187) Polyclonal Antibody detects endogenous levels of Kv1.3 protein only when phosphorylated at Y187. |
Additional Info
| Function | Isoform 1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 3: Lacks voltage-gated potassium channel activity. |
| Protein Name | Potassium Voltage-Gated Channel Subfamily A Member 3Hgk5Hlk3Hpcn3Voltage-Gated K(+ Channel HukiiiVoltage-Gated Potassium Channel Subunit Kv1.3 |
| Database Links | Reactome: R-HSA-1296072 |
| Cellular Localisation | Isoform 1: Cell MembraneMulti-Pass Membrane ProteinIsoform 2: Cell MembraneIsoform 3: CytoplasmPerinuclear Region |
| Alternative Antibody Names | Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 antibodyAnti-Hgk5 antibodyAnti-Hlk3 antibodyAnti-Hpcn3 antibodyAnti-Voltage-Gated K(+ Channel Hukiii antibodyAnti-Voltage-Gated Potassium Channel Subunit Kv1.3 antibodyAnti-KCNA3 antibodyAnti-HGK5 antibody |
Information sourced from Uniprot.org