Anti-Phospho-KCNA3-Tyr187 antibody (101-150 aa) (STJ91099)

SKU:
STJ91099
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Phospho-Potassium voltage-gated channel subfamily A member 3 channel HuKIII-Tyr187 (101-150 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related rea
Applications:WB/IHC/IF/ELISA
Host:Rabbit
Reactivity:Human/Mouse/Rat
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:KCNA3
Gene ID:3738
Uniprot ID:KCNA3_HUMAN
Immunogen:The antiserum was produced against synthesized peptide derived from the human Kv1.3/KCNA3 around the phosphorylation site of Tyr135 at the amino acid range 101-150
Immunogen Region:101-150 aa
Specificity:Phospho-Kv1.3 (Y187) Polyclonal Antibody detects endogenous levels of Kv1.3 protein only when phosphorylated at Y187.
Function Isoform 1: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 2: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Isoform 3: Lacks voltage-gated potassium channel activity.
Protein Name Potassium Voltage-Gated Channel Subfamily A Member 3
Hgk5
Hlk3
Hpcn3
Voltage-Gated K(+ Channel Hukiii
Voltage-Gated Potassium Channel Subunit Kv1.3
Database Links Reactome: R-HSA-1296072
Cellular Localisation Isoform 1: Cell Membrane
Multi-Pass Membrane Protein
Isoform 2: Cell Membrane
Isoform 3: Cytoplasm
Perinuclear Region
Alternative Antibody Names Anti-Potassium Voltage-Gated Channel Subfamily A Member 3 antibody
Anti-Hgk5 antibody
Anti-Hlk3 antibody
Anti-Hpcn3 antibody
Anti-Voltage-Gated K(+ Channel Hukiii antibody
Anti-Voltage-Gated Potassium Channel Subunit Kv1.3 antibody
Anti-KCNA3 antibody
Anti-HGK5 antibody

Information sourced from Uniprot.org