Anti-Phospho-IL7R-Tyr449 antibody (410-459 aa) (STJ90721)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human IL-7R/CD127 around the phosphorylation site of Tyr449 at the amino acid range 410-459
General Information
| Short Description | Rabbit polyclonal anti-Phospho-Interleukin-7 receptor subunit alpha-Tyr449 (410-459 aa) for use in WB, IF and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | IL7R |
| Gene ID | 3575 |
| Uniprot ID | IL7RA_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human IL-7R/CD127 around the phosphorylation site of Tyr449 at the amino acid range 410-459 |
| Immunogen Region | 410-459 aa |
| Specificity | Phospho-IL-7R (Y449) Polyclonal Antibody detects endogenous levels of IL-7R protein only when phosphorylated at Y449. |
Additional Info
| Function | Receptor for interleukin-7. Also acts as a receptor for thymic stromal lymphopoietin (TSLP). |
| Protein Name | Interleukin-7 Receptor Subunit AlphaIl-7 Receptor Subunit AlphaIl-7r Subunit AlphaIl-7r-AlphaIl-7raCdw127Cd Antigen Cd127 |
| Database Links | Reactome: R-HSA-1266695Reactome: R-HSA-8856825Reactome: R-HSA-8856828 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 3: Cell MembraneIsoform 4: Secreted |
| Alternative Antibody Names | Anti-Interleukin-7 Receptor Subunit Alpha antibodyAnti-Il-7 Receptor Subunit Alpha antibodyAnti-Il-7r Subunit Alpha antibodyAnti-Il-7r-Alpha antibodyAnti-Il-7ra antibodyAnti-Cdw127 antibodyAnti-Cd Antigen Cd127 antibodyAnti-IL7R antibody |
Information sourced from Uniprot.org