Name: Anti-Phospho-Gamma-H2AX-S139 antibody [C6] (STJA0019151)
SKU: STJA0019151
Availability: InStock

General Information
Product Properties
Target Information
Additional Info
Product Review

Host:	Mouse
Applications:	IHC/IP/WB
Reactivity:	Human
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS
Short Description :	Mouse monoclonal antibody anti-Phospho-Histone H2ax-S139 is suitable for use in Immunohistochemistry, Immunoprecipitation and Western Blot research applications.

Clonality :	Monoclonal
Clone ID :	C6
Conjugation:	Unconjugated
Isotype:	VHH-mFc
Formulation:	0.01M PBS
Purification:	Protein A/G purified from cell culture supernatant
Concentration:	1 mg/mL
Storage Instruction:	Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months

Gene Symbol:	H2AX
Gene ID:	3014
Uniprot ID:	H2AX_HUMAN

Function	Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Protein Name	Histone H2ax H2a/X Histone H2a.x
Database Links	Reactome: R-HSA-110328 Reactome: R-HSA-110329 Reactome: R-HSA-110330 Reactome: R-HSA-110331 Reactome: R-HSA-1221632 Reactome: R-HSA-171306 Reactome: R-HSA-1912408 Reactome: R-HSA-201722 Reactome: R-HSA-212300 Reactome: R-HSA-2299718 Reactome: R-HSA-2559580 Reactome: R-HSA-2559582 Reactome: R-HSA-2559586 Reactome: R-HSA-3214858 Reactome: R-HSA-427359 Reactome: R-HSA-427389 Reactome: R-HSA-427413 Reactome: R-HSA-5250924 Reactome: R-HSA-5334118 Reactome: R-HSA-5578749 Reactome: R-HSA-5617472 Reactome: R-HSA-5625886 Reactome: R-HSA-5693565 Reactome: R-HSA-5693571 Reactome: R-HSA-5693607 Reactome: R-HSA-606279 Reactome: R-HSA-68616 Reactome: R-HSA-69473 Reactome: R-HSA-73728 Reactome: R-HSA-73772 Reactome: R-HSA-8936459 Reactome: R-HSA-8939236 Reactome: R-HSA-9018519 Reactome: R-HSA-912446 Reactome: R-HSA-9616222 Reactome: R-HSA-9670095 Reactome: R-HSA-9710421 Reactome: R-HSA-977225 Reactome: R-HSA-9821002 Reactome: R-HSA-9821993 Reactome: R-HSA-9843940 Reactome: R-HSA-9843970 Reactome: R-HSA-9845323
Cellular Localisation	Nucleus Chromosome
Alternative Antibody Names	Anti-Histone H2ax antibody Anti-H2a/X antibody Anti-Histone H2a.x antibody Anti-H2AX antibody Anti-H2AFX antibody

Information sourced from Uniprot.org

Model	Name	Host	Clonality	Reactivity	Application
STJA0019679	Anti-Phospho-Gamma-H2AX-S139 antibody [9F3] (STJA0019679)	Mouse	Monoclonal	Human	IHC/WB
STJA0019152	Anti-Phospho-Gamma-H2AX-S139 antibody [A9] (STJA0019152)	Mouse	Monoclonal	Human	IHC/IP/WB
STJA0019154	Anti-Phospho-Gamma-H2AX-S139 antibody [G2] (STJA0019154)	Mouse	Monoclonal	Human	IF/IHC/IP/WB
STJA0019153	Anti-Phospho-Gamma-H2AX-S139 antibody [A4] (STJA0019153)	Mouse	Monoclonal	Human	IHC/IP/WB
STJ11107702	Anti-Phospho-H2AX-S139 antibody (STJ11107702)	Rabbit	Polyclonal	A.thaliana	WB/ELISA

Anti-Phospho-Gamma-H2AX-S139 antibody [C6] (STJA0019151)

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