• Western blot analysis of lysates from HUVEC cells, using Catenin-delta1 (Phospho-Tyr228) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunohistochemistry analysis of paraffin-embedded human brain, using Catenin-delta1 (Phospho-Tyr228) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of 293T cells using Phospho-p120 (Y228) Polyclonal Antibody diluted at 1：500
  • Immunofluorescence analysis of HUVEC cells, using Catenin-delta1 (Phospho-Tyr228) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of various cells using Phospho-p120 (Y228) Polyclonal Antibody diluted at 1：500

Anti-Phospho-CTNND1-Tyr228 antibody (201-250 aa) (STJ91079)

SKU:
STJ91079

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Catenin delta-1-Tyr228 (201-250 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:10000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CTNND1
Gene ID: 1500
Uniprot ID: CTND1_HUMAN
Immunogen Region: 201-250 aa
Specificity: Phospho-p120 (Y228) Polyclonal Antibody detects endogenous levels of p120 protein only when phosphorylated at Y228.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Catenin-delta1 around the phosphorylation site of Tyr228 at the amino acid range 201-250
Post Translational Modifications Phosphorylated by FER and other protein-tyrosine kinases. Phosphorylated at Ser-288 by PAK5. Dephosphorylated by PTPRJ.
Function Key regulator of cell-cell adhesion that associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Beside cell-cell adhesion, regulates gene transcription through several transcription factors including ZBTB33/Kaiso2 and GLIS2, and the activity of Rho family GTPases and downstream cytoskeletal dynamics. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
Protein Name Catenin Delta-1
Cadherin-Associated Src Substrate
Cas
P120 Catenin
P120(Ctn
P120(Cas
Database Links Reactome: R-HSA-418990
Reactome: R-HSA-5218920
Reactome: R-HSA-8876493
Reactome: R-HSA-9762292
Reactome: R-HSA-9764302
Reactome: R-HSA-9833576
Cellular Localisation Cell Junction
Adherens Junction
Cytoplasm
Nucleus
Cell Membrane
Interaction With Glis2 Promotes Nuclear Translocation
Detected At Cell-Cell Contacts
Nanos1 Induces Its Translocation From Sites Of Cell-Cell Contact To The Cytoplasm
Cdh1 Enhances Cell Membrane Localization
Isoforms 4a And 1ab Are Excluded From The Nucleus
Isoform 1a: Nucleus
Isoform 2a: Nucleus
Isoform 3a: Nucleus
Alternative Antibody Names Anti-Catenin Delta-1 antibody
Anti-Cadherin-Associated Src Substrate antibody
Anti-Cas antibody
Anti-P120 Catenin antibody
Anti-P120(Ctn antibody
Anti-P120(Cas antibody
Anti-CTNND1 antibody
Anti-KIAA0384 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance