Anti-Phospho-CDC25A-Ser75 antibody (STJ90215)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized phospho-peptide around the phosphorylation site of human Cdc25A (phospho Ser75)
STJ90215
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General Information

Short DescriptionRabbit polyclonal anti-Phospho-M-phase inducer phosphatase 1-Ser75 for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC/IF/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCDC25A
Gene ID993
Uniprot IDMPIP1_HUMAN
ImmunogenSynthesized phospho-peptide around the phosphorylation site of human Cdc25A (phospho Ser75)
SpecificityPhospho-Cdc25A (S75) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S75.

Additional Info

Function Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin-E, in vitro.
Protein Name M-Phase Inducer Phosphatase 1
Dual Specificity Phosphatase Cdc25a
Database Links Reactome: R-HSA-1362277
Reactome: R-HSA-156711
Reactome: R-HSA-176187
Reactome: R-HSA-5689880
Reactome: R-HSA-69202
Reactome: R-HSA-69273
Reactome: R-HSA-69601
Reactome: R-HSA-69656
Reactome: R-HSA-8862803
Cellular Localisation
Alternative Antibody Names Anti-M-Phase Inducer Phosphatase 1 antibody
Anti-Dual Specificity Phosphatase Cdc25a antibody
Anti-CDC25A antibody

Information sourced from Uniprot.org

Citations

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