Anti-Phospho-CDC25A-Ser75 antibody (43-92 aa) (STJ90216)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser75 at the amino acid range 43-92
General Information
| Short Description | Rabbit polyclonal anti-Phospho-M-phase inducer phosphatase 1-Ser75 (43-92 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CDC25A |
| Gene ID | 993 |
| Uniprot ID | MPIP1_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CDC25A around the phosphorylation site of Ser75 at the amino acid range 43-92 |
| Immunogen Region | 43-92 aa |
| Specificity | Phospho-Cdc25A (S75) Polyclonal Antibody detects endogenous levels of Cdc25A protein only when phosphorylated at S75. |
Additional Info
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin-E, in vitro. |
| Protein Name | M-Phase Inducer Phosphatase 1Dual Specificity Phosphatase Cdc25a |
| Database Links | Reactome: R-HSA-1362277Reactome: R-HSA-156711Reactome: R-HSA-176187Reactome: R-HSA-5689880Reactome: R-HSA-69202Reactome: R-HSA-69273Reactome: R-HSA-69601Reactome: R-HSA-69656Reactome: R-HSA-8862803 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-M-Phase Inducer Phosphatase 1 antibodyAnti-Dual Specificity Phosphatase Cdc25a antibodyAnti-CDC25A antibody |
Information sourced from Uniprot.org