Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Mouse/Rat |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description : | Rabbit polyclonal antibody anti-Phospho-G2/mitotic-specific cyclin-B1-Ser147 (121-170 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality : | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | WB 1:500-1:2000 IHC 1:100-1:300 ELISA 1:10000 IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: | CCNB1 |
Gene ID: | 891 |
Uniprot ID: | CCNB1_HUMAN |
Immunogen Region: | 121-170 aa |
Specificity: | Phospho-Cyclin B1 (S147) Polyclonal Antibody detects endogenous levels of Cyclin B1 protein only when phosphorylated at S147. |
Immunogen: | The antiserum was produced against synthesized peptide derived from the human Cyclin B1 around the phosphorylation site of Ser147 at the amino acid range 121-170 |
Function | Essential for the control of the cell cycle at the G2/M (mitosis) transition. |
Protein Name | G2/Mitotic-Specific Cyclin-B1 |
Database Links | Reactome: R-HSA-113507 Reactome: R-HSA-156711 Reactome: R-HSA-162658 Reactome: R-HSA-174048 Reactome: R-HSA-176408 Reactome: R-HSA-176412 Reactome: R-HSA-176417 Reactome: R-HSA-2299718 Reactome: R-HSA-2465910 Reactome: R-HSA-2500257 Reactome: R-HSA-2514853 Reactome: R-HSA-2565942 Reactome: R-HSA-2980767 Reactome: R-HSA-2995383 Reactome: R-HSA-3301854 Reactome: R-HSA-4419969 Reactome: R-HSA-6804114 Reactome: R-HSA-68875 Reactome: R-HSA-69273 Reactome: R-HSA-69478 Reactome: R-HSA-75035 Reactome: R-HSA-8852276 Reactome: R-HSA-8878166 Reactome: R-HSA-9725371 Reactome: R-HSA-9825892 |
Cellular Localisation | Cytoplasm Nucleus Cytoskeleton Microtubule Organizing Center Centrosome |
Alternative Antibody Names | Anti-G2/Mitotic-Specific Cyclin-B1 antibody Anti-CCNB1 antibody Anti-CCNB antibody |
Information sourced from Uniprot.org