Anti-Phospho-ATRIP-Ser68 antibody (34-83 aa) (STJ90496)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human ATRIP around the phosphorylation site of Ser68 at the amino acid range 34-83
General Information
| Short Description | Rabbit polyclonal anti-Phospho-ATR-interacting protein-Ser68 (34-83 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATRIP |
| Gene ID | 84126 |
| Uniprot ID | ATRIP_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human ATRIP around the phosphorylation site of Ser68 at the amino acid range 34-83 |
| Immunogen Region | 34-83 aa |
| Specificity | Phospho-ATRIP (S68) Polyclonal Antibody detects endogenous levels of ATRIP protein only when phosphorylated at S68. |
Additional Info
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. |
| Protein Name | Atr-Interacting ProteinAtm And Rad3-Related-Interacting Protein |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-5685938Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-6783310Reactome: R-HSA-6804756Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | NucleusRedistributes To Discrete Nuclear Foci Upon Dna Damage |
| Alternative Antibody Names | Anti-Atr-Interacting Protein antibodyAnti-Atm And Rad3-Related-Interacting Protein antibodyAnti-ATRIP antibodyAnti-AGS1 antibody |
Information sourced from Uniprot.org