Anti-Phospho-ATRIP-Ser239 antibody (STJA0003585)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 conjugated to KLH.
General Information
| Short Description | Rabbit polyclonal anti-Phospho-ATRIP-Ser239 for use in WB in Mouse, Bovine, Human, Non-Human Primates and Sheep samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Mouse/Bovine/Human/Non-Human Primates/Sheep |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | This antibody was antigen affinity purified from pooled serum. |
| Dilution Range | WB 1:500 |
| Formulation | 100 µl in 10 mM HEPES (pH 7.5) , 150 mM NaCl, 100 µg per ml BSA and 50% Glycerol. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATRIP |
| Gene ID | 84126 |
| Uniprot ID | ATRIP_HUMAN |
| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser239 conjugated to KLH. |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylated by ATR. |
| Function | Required for checkpoint signaling after DNA damage. Required for ATR expression, possibly by stabilizing the protein. |
| Protein Name | Atr-Interacting ProteinAtm And Rad3-Related-Interacting Protein |
| Database Links | Reactome: R-HSA-176187Reactome: R-HSA-5685938Reactome: R-HSA-5693607Reactome: R-HSA-5693616Reactome: R-HSA-6783310Reactome: R-HSA-6804756Reactome: R-HSA-69473Reactome: R-HSA-9709570 |
| Cellular Localisation | NucleusRedistributes To Discrete Nuclear Foci Upon Dna Damage |
| Alternative Antibody Names | Anti-Atr-Interacting Protein antibodyAnti-Atm And Rad3-Related-Interacting Protein antibodyAnti-ATRIP antibodyAnti-AGS1 antibody |
Information sourced from Uniprot.org