• Immunohistochemistry analysis of paraffin-embedded human brain, using APC1 (Phospho-Ser355) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-ANAPC1-Ser355 antibody (321-370 aa) (STJ91228)

SKU:
STJ91228

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Anaphase-promoting complex subunit 1-Ser355 (321-370 aa) is suitable for use in Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC 1:100-1:300
ELISA 1:5000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ANAPC1
Gene ID: 64682
Uniprot ID: APC1_HUMAN
Immunogen Region: 321-370 aa
Specificity: Phospho-APC1 (S355) Polyclonal Antibody detects endogenous levels of APC1 protein only when phosphorylated at S355.
Immunogen: The antiserum was produced against synthesized peptide derived from the human APC1 around the phosphorylation site of Ser355 at the amino acid range 321-370
Function Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Protein Name Anaphase-Promoting Complex Subunit 1
Apc1
Cyclosome Subunit 1
Mitotic Checkpoint Regulator
Testis-Specific Gene 24 Protein
Database Links Reactome: R-HSA-141430
Reactome: R-HSA-174048
Reactome: R-HSA-174084
Reactome: R-HSA-174154
Reactome: R-HSA-174178
Reactome: R-HSA-174184
Reactome: R-HSA-176407
Reactome: R-HSA-176408
Reactome: R-HSA-176409
Reactome: R-HSA-176412
Reactome: R-HSA-179409
Reactome: R-HSA-2467813
Reactome: R-HSA-2559582
Reactome: R-HSA-68867
Reactome: R-HSA-69017
Reactome: R-HSA-8853884
Reactome: R-HSA-9687136
Reactome: R-HSA-983168
Alternative Antibody Names Anti-Anaphase-Promoting Complex Subunit 1 antibody
Anti-Apc1 antibody
Anti-Cyclosome Subunit 1 antibody
Anti-Mitotic Checkpoint Regulator antibody
Anti-Testis-Specific Gene 24 Protein antibody
Anti-ANAPC1 antibody
Anti-TSG24 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance