| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-Phospho-Akt is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | LP18 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b |
| Formulation: | Tissue culture supernatant with 15mM sodium azide |
| Concentration: | >=300 mg/L |
| Storage Instruction: | Store at 2-8°C upon receipt. |
| Immunogen: | A chemically synthesized phosphorylated peptide corresponding to residues around Ser473 of the human Akt molecule. |
| Background | Akt-1, also referred to as protein kinase B (PKB) or Rac alpha is a member of the Akt serin/threonine protein kinase family. It plays an important role in many biological responses including metabolism, cell survival and growth by phosphorylation and inactivating several targets including GSK 3 beta, caspase 9, BAD and the forkhead transcription factor. Akt-Phos is not recommended for use with PBS, since the use of PBS-based wash buffers and possibly PBS-based antibody diluents gives increased background staining and decreased staining intensity. |
Information sourced from Uniprot.org

