• Immunohistochemistry analysis of paraffin-embedded human brain, using Adrenergic Receptor beta2 (Phospho-Ser346) Antibody. The picture on the right is blocked with the phospho peptide.
  • Western blot analysis of lysates from HepG2 cells treated with nocodazole 1ug/ml 16h, using Adrenergic Receptor beta2 (Phospho-Ser346) Antibody. The lane on the right is blocked with the phospho peptide.
  • Immunofluorescence analysis of HeLa cells, using Adrenergic Receptor beta2 (Phospho-Ser346) Antibody. The picture on the right is blocked with the phospho peptide.

Anti-Phospho-ADRB2-Ser346 antibody (321-370 aa) (STJ91102)

SKU:
STJ91102

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Phospho-Beta-2 adrenergic receptor-Ser346 (321-370 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:20000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: ADRB2
Gene ID: 154
Uniprot ID: ADRB2_HUMAN
Immunogen Region: 321-370 aa
Specificity: Phospho-AR-Beta 2 (S346) Polyclonal Antibody detects endogenous levels of AR-Beta 2 protein only when phosphorylated at S346.
Immunogen: The antiserum was produced against synthesized peptide derived from the human Adrenergic Receptor beta2 around the phosphorylation site of Ser346 at the amino acid range 321-370
Function Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.
Protein Name Beta-2 Adrenergic Receptor
Beta-2 Adrenoreceptor
Beta-2 Adrenoceptor
Database Links Reactome: R-HSA-390696
Reactome: R-HSA-418555
Reactome: R-HSA-5689880
Reactome: R-HSA-8856825
Reactome: R-HSA-8856828
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Early Endosome
Golgi Apparatus
Colocalizes With Vhl At The Cell Membrane
Activated Receptors Are Internalized Into Endosomes Prior To Their Degradation In Lysosomes
Activated Receptors Are Also Detected Within The Golgi Apparatus
Alternative Antibody Names Anti-Beta-2 Adrenergic Receptor antibody
Anti-Beta-2 Adrenoreceptor antibody
Anti-Beta-2 Adrenoceptor antibody
Anti-ADRB2 antibody
Anti-ADRB2R antibody
Anti-B2AR antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance