| Short Description : | Rabbit polyclonal anti-Phospho-ATP-citrate synthase-lyase-Ser455 (420-469 aa) for use in WB, IHC, IF and ELISA in Human, Mouse, Rat and Monkey samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC/IF/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat/Monkey |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-1:2000IHC 1:100-1:300ELISA 1:10000IF 1:50-200 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | ACLY |
| Gene ID: | 47 |
| Uniprot ID: | ACLY_HUMAN |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human ATP-Citrate Lyase around the phosphorylation site of Ser454 at the amino acid range 420-469 |
| Immunogen Region: | 420-469 aa |
| Specificity: | Phospho-ATP-citrate synthase (S455) Polyclonal Antibody detects endogenous levels of ATP-citrate synthase protein only when phosphorylated at S455. |
| Function | Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate in multiple biochemical reactions in protein, carbohydrate and lipid metabolism. |
| Protein Name | Atp-Citrate SynthaseAtp-CitratePro-S--LyaseAclCitrate Cleavage Enzyme |
| Database Links | Reactome: R-HSA-163765Reactome: R-HSA-6798695Reactome: R-HSA-75105 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-Atp-Citrate Synthase antibodyAnti-Atp-Citrate antibodyAnti-Pro-S--Lyase antibodyAnti-Acl antibodyAnti-Citrate Cleavage Enzyme antibodyAnti-ACLY antibody |
Information sourced from Uniprot.org
