Anti-PHKA2 antibody (911-961 aa) (STJ195331)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human KPB2 at the amino acid range 911-961
STJ195331
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General Information

Short DescriptionRabbit polyclonal anti-Phosphorylase b kinase regulatory subunit alpha, liver isoform (911-961 aa) for use in WB and IHC in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IHC
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
Concentration1 mg/mL
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution RangeWB 1:500-2000
IHC-P 1:50-300
FormulationLiquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPHKA2
Gene ID5256
Uniprot IDKPB2_HUMAN
ImmunogenSynthesized peptide derived from the human KPB2 at the amino acid range 911-961
Immunogen Region911-961 aa
SpecificityThis antibody detects endogenous levels of KPB2 at Human/Mouse

Additional Info

Post Translational Modifications Although the final Cys may be farnesylated, the terminal tripeptide is probably not removed, and the C-terminus is not methylated.
Function Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
Protein Name Phosphorylase B Kinase Regulatory Subunit Alpha - Liver Isoform
Phosphorylase Kinase Alpha L Subunit
Database Links Reactome: R-HSA-70221
Cellular Localisation Cell Membrane
Lipid-Anchor
Cytoplasmic Side
Alternative Antibody Names Anti-Phosphorylase B Kinase Regulatory Subunit Alpha - Liver Isoform antibody
Anti-Phosphorylase Kinase Alpha L Subunit antibody
Anti-PHKA2 antibody
Anti-PHKLA antibody
Anti-PYK antibody

Information sourced from Uniprot.org

Citations

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