Anti-PHF20 antibody (STJA0008246)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PHF20
General Information
| Short Description | Rabbit polyclonal anti-PHD finger protein 20 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PHF20 |
| Gene ID | 51230 |
| Uniprot ID | PHF20_HUMAN |
| Immunogen | Synthesized peptide derived from human PHF20 |
| Specificity | This antibody detects endogenous levels of PHF20 at Human, Mouse |
Additional Info
| Post Translational Modifications | Ubiquitinated by TRIM26.leading to proteasomal degradation. |
| Function | Methyllysine-binding protein, component of the MOF histone acetyltransferase protein complex. Not required for maintaining the global histone H4 'Lys-16' acetylation (H4K16ac) levels or locus specific histone acetylation, but instead works downstream in transcriptional regulation of MOF target genes. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. Contributes to methyllysine-dependent p53/TP53 stabilization and up-regulation after DNA damage. |
| Protein Name | Phd Finger Protein 20Glioma-Expressed Antigen 2Hepatocellular Carcinoma-Associated Antigen 58Novel Zinc Finger ProteinTranscription Factor Tzp |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-6804757Reactome: R-HSA-6804759Reactome: R-HSA-69541Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Phd Finger Protein 20 antibodyAnti-Glioma-Expressed Antigen 2 antibodyAnti-Hepatocellular Carcinoma-Associated Antigen 58 antibodyAnti-Novel Zinc Finger Protein antibodyAnti-Transcription Factor Tzp antibodyAnti-PHF20 antibodyAnti-C20orf104 antibodyAnti-GLEA2 antibodyAnti-HCA58 antibodyAnti-NZF antibodyAnti-TZP antibody |
Information sourced from Uniprot.org