| Short Description : | Rabbit polyclonal anti-Phosphatase and actin regulator 1 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: | WB 1:500-2000 |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PHACTR1 |
| Gene ID: | 221692 |
| Uniprot ID: | PHAR1_HUMAN |
| Immunogen: | Synthesized peptide derived from human PHACTR1 |
| Specificity: | This antibody detects endogenous levels of PHACTR1 at Human, Mouse, Rat |
| Function | Binds actin monomers (G actin) and plays a role in multiple processes including the regulation of actin cytoskeleton dynamics, actin stress fibers formation, cell motility and survival, formation of tubules by endothelial cells, and regulation of PPP1CA activity. Involved in the regulation of cortical neuron migration and dendrite arborization. |
| Protein Name | Phosphatase And Actin Regulator 1 |
| Database Links | |
| Cellular Localisation | CytoplasmSynapseNucleusEnriched At SynapsesCytoplasmic In Resting CellsAnd Is Imported Into The Nucleus Upon Serum StimulationInteraction With Actin Prevents Nuclear Import |
| Alternative Antibody Names | Anti-Phosphatase And Actin Regulator 1 antibodyAnti-PHACTR1 antibodyAnti-KIAA1733 antibodyAnti-RPEL1 antibody |
Information sourced from Uniprot.org
