Anti-PGCE antibody (C-Term) {FITC} (STJ502467)

SKU:
STJ502467-100

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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PGCE (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: FITC
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.75-1.20 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IHC: 1:200
ICC: 1:200
IF: 1:200
CFM: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Gucy2e
Gene ID: 79222
Uniprot ID: GUC2E_RAT
Immunogen Region: C-Term
Immunogen: Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase E protein.
Tissue Specificity Expressed in retina and enriched in photoreceptor outer segments.
Post Translational Modifications There are 9 conserved cysteine residues in sensory guanylate cyclases, 6 in the extracellular domain, which may be involved in intra- or interchain disulfide bonds.
Function Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment. May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane.
Protein Name Retinal Guanylyl Cyclase 1
Retgc-1
Guanylate Cyclase 2e
Guanylyl Cyclase Gc-E
Database Links Reactome: R-RNO-2514859
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Photoreceptor Outer Segment Membrane
Endoplasmic Reticulum Membrane
Alternative Antibody Names Anti-Retinal Guanylyl Cyclase 1 antibody
Anti-Retgc-1 antibody
Anti-Guanylate Cyclase 2e antibody
Anti-Guanylyl Cyclase Gc-E antibody
Anti-Gucy2e antibody
Anti-Guc2e antibody
Anti-Gucy2d antibody

Information sourced from Uniprot.org

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