• Immunohistochemistry of baboon small intestine with Anti-PGCD primary antibody (STJ502462) at 1:100 dilution in Buffer. Section was treated with DAB and Haematoxylin stain. Magnification is at 40X.

Anti-PGCD antibody (C-Term) (STJ502462)

SKU:
STJ502462-100

£441.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PGCD (C-Term) is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.75-1.20 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
IHC: 1:200
ICC: 1:200
IF: 1:200
CFM: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Gucy2d
Gene ID: 113911
Uniprot ID: GUC2D_RAT
Immunogen Region: C-Term
Immunogen: Synthetic C-terminal peptide corresponding to unique amino acid sequences on Particulate Guanylyl Cyclase D protein.
Tissue Specificity Specifically expressed in a subpopulation of olfactory sensory neurons. Expressed in the cilia of the olfactory epithelium.
Function Functions as an olfactory receptor activated by a urine odorant, uroguanylin. Activated as well by the volatile semiochemicals carbon disulfide (CS2) and carbon dioxide (CO2). Has guanylate cyclase activity upon binding of the ligand. Activation of GUCY2D neurons leads to the cGMP-dependent activation of the CNGA3 channels, membrane depolarization and an increase in action potential frequency. Signaling pathways activated by GUCY2D may trigger social behaviors such as acquisition of food preference.
Protein Name Guanylate Cyclase 2d
Guanylate Cyclase - Olfactory
One-Gc
Olfactory Guanylyl Cyclase Gc-D
Gc-D
Cellular Localisation Cell Projection
Cilium Membrane
Single-Pass Type I Membrane Protein
Colocalized With Ncald At The Apical Region Of The Cilia
Coexpresses With Pde2
Alternative Antibody Names Anti-Guanylate Cyclase 2d antibody
Anti-Guanylate Cyclase - Olfactory antibody
Anti-One-Gc antibody
Anti-Olfactory Guanylyl Cyclase Gc-D antibody
Anti-Gc-D antibody
Anti-Gucy2d antibody
Anti-Gucy2e antibody

Information sourced from Uniprot.org

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