Anti-PFN2 antibody (100-140) (STJ24965)

Name: Anti-PFN2 antibody (100-140) (STJ24965)
SKU: STJ24965
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ24965

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Short Description	Rabbit polyclonal PFN2 (100-140) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	PFN2
Gene ID	5217
Uniprot ID	PROF2_HUMAN
Immunogen Region	100-140
Immunogen Sequence	NVAVGRAGRVLVFVMGKEGV HGGGLNKKAYSMAKYLRDSG F
Specificity	A synthetic peptide corresponding to a sequence within amino acids 100-140 of human PFN2 (P35080).

Tissue Specificity	Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
Function	Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
Protein Name	Profilin-2 Profilin Ii
Database Links	Reactome: R-HSA-376176 Reactome: R-HSA-5663220
Cellular Localisation	Cytoplasm Cytoskeleton
Alternative Antibody Names	Anti-Profilin-2 antibody Anti-Profilin Ii antibody Anti-PFN2 antibody

Information sourced from Uniprot.org