Anti-PFKFB3 antibody (1-210) (STJ116964)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal PFKFB3 (1-210) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PFKFB3 |
| Gene ID | 5209 |
| Uniprot ID | F263_HUMAN |
| Immunogen Region | 1-210 |
| Immunogen Sequence | MPLELTQSRVQKIWVPVDHR PSLPRSCGPKLTNSPTVIVM VGLPARGKTYISKKLTRYLN WIGVPTKVFNVGEYRREAVK QYSSYNFFRPDNEEAMKVRK QCALAALRDVKSYLAKEGGQ IAVFDATNTTRERRHMILHF AKENDFKAFFIESVCDDPTV VASNIMEVKISSPDYKDCNS AEAMDDFMKRISCYEASYQP LDPDKCDRDL |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PFKFB3 (NP_004557.1). |
Additional Info
| Tissue Specificity | Ubiquitous. |
| Post Translational Modifications | Phosphorylation by AMPK stimulates activity. |
| Function | Catalyzes both the synthesis and degradation of fructose 2,6-bisphosphate. |
| Protein Name | 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 36pf-2-K/Fru-2 -6-P2ase 3Pfk/Fbpase 36pf-2-K/Fru-2 -6-P2ase Brain/Placenta-Type IsozymeRenal Carcinoma Antigen Ny-Ren-56Ipfk-2 Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase |
| Database Links | Reactome: R-HSA-9634600 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 3 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase 3 antibodyAnti-Pfk/Fbpase 3 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase Brain/Placenta-Type Isozyme antibodyAnti-Renal Carcinoma Antigen Ny-Ren-56 antibodyAnti-Ipfk-2 Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibodyAnti-PFKFB3 antibody |
Information sourced from Uniprot.org