| Host: | Goat |
| Applications: | Pep-ELISA/IHC |
| Reactivity: | Human/Dog/Cow |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Goat polyclonal antibody anti-PFKFB2 (N-Term) is suitable for use in ELISA and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: | 0.5 mg/mL |
| Dilution Range: | Peptide ELISA: antibody detection limit dilution 1:16000.WB: Preliminary experiments gave an approx 75Da band in Human Heart lysates after 1µg/ml antibody staining. Please note that currently we cannot find an explanation in the literature for t |
| Storage Instruction: | Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: | PFKFB2 |
| Gene ID: | 5208 |
| Uniprot ID: | F262_HUMAN |
| Immunogen Region: | N-Term |
| Accession Number: | NP_006203.2; NP_001018063.1 |
| Specificity: | This antibody is expected to recognize both reported isoforms (NP_006203.2; NP_001018063.1). |
| Immunogen Sequence: | SEQNNNSYETKTP |
| Post Translational Modifications | Phosphorylation by AMPK stimulates activity. |
| Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
| Protein Name | 6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 26pf-2-K/Fru-2 -6-P2ase 2Pfk/Fbpase 26pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase |
| Database Links | Reactome: R-HSA-9634600 |
| Alternative Antibody Names | Anti-6-Phosphofructo-2-Kinase/Fructose-2 -6-Bisphosphatase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase 2 antibodyAnti-Pfk/Fbpase 2 antibodyAnti-6pf-2-K/Fru-2 -6-P2ase Heart-Type Isozyme Includes - 6-Phosphofructo-2-Kinase - Fructose-2 -6-Bisphosphatase antibodyAnti-PFKFB2 antibody |
Information sourced from Uniprot.org