Confocal imaging of HeLa cells usingย PFDN5 Rabbit monoclonal antibody (STJ11103552, dilution 1:100) followed by a further incubation with Cy3 Goat Anti-Rabbit IgG (H+L) ( dilution 1:500) (Red). The cells were counterstained with Alpha-Tubulin Mouse monoclonal antibody ( dilution 1:400) followed by incubation with ABfloยฎ 488-conjugated Goat Anti-Mouse IgG (H+L) antibody ( dilution 1:500) (Green). DAPI was used for nuclear staining (Blue). Objective: 100x.

Anti-PFDN5 antibody (50-154) [S2MR] (STJ11103552)

⇓ Datasheet ⇓ SDS
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ11103552
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General Information

Short DescriptionRabbit monoclonal PFDN5 (50-154) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF/ICC/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDS2MR
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:1000
IF/ICC:1:50-1:200
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolPFDN5
Gene ID5204
Uniprot IDPFD5_HUMAN
Immunogen Region50-154
Immunogen SequenceLNVLNKSNEGKELLVPLTSS MYVPGKLHDVEHVLIDVGTG YYVEKTAEDAKDFFKRKIDF LTKQMEKIQPALQEKHAMKQ AVMEMMSQKIQQLTALGAAQ ATAKA
SpecificityA synthetic peptide corresponding to a sequence within amino acids 50-154 of human PFDN5 (Q99471).

Additional Info

Tissue Specificity Highly expressed in pancreas and skeletal muscle and moderately in other tissues.
Function Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC.
Protein Name Prefoldin Subunit 5
Myc Modulator 1
C-Myc-Binding Protein Mm-1
Database Links Reactome: R-HSA-389957
Cellular Localisation Isoform 1: Nucleus
Isoform 2: Cytoplasm
Isoform 3: Nucleus
Alternative Antibody Names Anti-Prefoldin Subunit 5 antibody
Anti-Myc Modulator 1 antibody
Anti-C-Myc-Binding Protein Mm-1 antibody
Anti-PFDN5 antibody
Anti-MM1 antibody
Anti-PFD5 antibody

Information sourced from Uniprot.org

Citations

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