| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S2MR |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PFDN5 |
| Gene ID: | 5204 |
| Uniprot ID: | PFD5_HUMAN |
| Immunogen Region: | 50-154 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 50-154 of human PFDN5 (Q99471). |
| Immunogen Sequence: | LNVLNKSNEGKELLVPLTSS MYVPGKLHDVEHVLIDVGTG YYVEKTAEDAKDFFKRKIDF LTKQMEKIQPALQEKHAMKQ AVMEMMSQKIQQLTALGAAQ ATAKA |
| Tissue Specificity | Highly expressed in pancreas and skeletal muscle and moderately in other tissues. |
| Function | Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins. Represses the transcriptional activity of MYC. |
| Protein Name | Prefoldin Subunit 5Myc Modulator 1C-Myc-Binding Protein Mm-1 |
| Database Links | Reactome: R-HSA-389957 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: CytoplasmIsoform 3: Nucleus |
| Alternative Antibody Names | Anti-Prefoldin Subunit 5 antibodyAnti-Myc Modulator 1 antibodyAnti-C-Myc-Binding Protein Mm-1 antibodyAnti-PFDN5 antibodyAnti-MM1 antibodyAnti-PFD5 antibody |
Information sourced from Uniprot.org