Anti-Peroxiredoxin 5 antibody [R04-2F9] (STJA0034710)

SKU:
STJA0034710
€160.20 - €337.80
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Host: Rabbit
Applications: WB/IHC-P/IP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-Peroxiredoxin 5 for use in WB, IHC-P and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R04-2F9
Conjugation: Unconjugated
Isotype: IgG
Formulation: 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Purification: Affinity Purified
Concentration: 0.3 mg/mL
Dilution Range: WB 1:500-1:1000
IHC 1:50-1:100
IP 1:20
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: PRDX5
Gene ID: 25824
Uniprot ID: PRDX5_HUMAN
Immunogen: A synthetic peptide of human Peroxiredoxin 5
Tissue Specificity Widely expressed.
Post Translational Modifications S-palmitoylated. Palmitoylation occurs on the active site, inhibiting its reactivity.therefore PRDX5 palmitoylation status determines its antioxidant capacity. Isoform Mitochondrial: S-palmitoylated. Depalmitoylated by ABHD10.
Function Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events.
Protein Name Peroxiredoxin-5 - Mitochondrial
Alu Corepressor 1
Antioxidant Enzyme B166
Aoeb166
Liver Tissue 2d-Page Spot 71b
Plp
Peroxiredoxin V
Prx-V
Peroxisomal Antioxidant Enzyme
Tpx Type Vi
Thioredoxin Peroxidase Pmp20
Thioredoxin-Dependent Peroxiredoxin 5
Database Links Reactome: R-HSA-3299685
Reactome: R-HSA-5628897 P30044-2
Cellular Localisation Isoform Mitochondrial: Mitochondrion
Isoform Cytoplasmic+Peroxisomal: Cytoplasm
Peroxisome Matrix
Imported Into Peroxisomes Via Peroxisomal Targeting Signal 1 Receptor Pex5
Alternative Antibody Names Anti-Peroxiredoxin-5 - Mitochondrial antibody
Anti-Alu Corepressor 1 antibody
Anti-Antioxidant Enzyme B166 antibody
Anti-Aoeb166 antibody
Anti-Liver Tissue 2d-Page Spot 71b antibody
Anti-Plp antibody
Anti-Peroxiredoxin V antibody
Anti-Prx-V antibody
Anti-Peroxisomal Antioxidant Enzyme antibody
Anti-Tpx Type Vi antibody
Anti-Thioredoxin Peroxidase Pmp20 antibody
Anti-Thioredoxin-Dependent Peroxiredoxin 5 antibody
Anti-PRDX5 antibody
Anti-ACR1 antibody
Anti-SBBI10 antibody

Information sourced from Uniprot.org