| Host: |
Goat |
| Applications: |
Pep-ELISA |
| Reactivity: |
Human/Pig |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-PEPT2 (C-Term) is suitable for use in ELISA research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
ELISA-antibody detection limit dilution 1:8000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
SLC15A2 |
| Gene ID: |
6565 |
| Uniprot ID: |
S15A2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_066568.2 |
| Immunogen Sequence: |
QGNMIKLETKKTK |
| Function | Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Transports neutral and anionic dipeptides with a proton to peptide stoichiometry of 2:1 or 3:1. In kidney, involved in the absorption of circulating di- and tripeptides from the glomerular filtrate. Can also transport beta-lactam antibiotics, such as the aminocephalosporin cefadroxil, and other antiviral and anticancer drugs. Transports the dipeptide-like aminopeptidase inhibitor bestatin. Also able to transport carnosine. Involved in innate immunity by promoting the detection of microbial pathogens by NOD-like receptors (NLRs). Mediates transport of bacterial peptidoglycans across the plasma membrane or, in macrophages, the phagosome membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand. |
| Protein Name | Solute Carrier Family 15 Member 2Kidney H(+/Peptide CotransporterOligopeptide Transporter - Kidney IsoformPeptide Transporter 2 |
| Database Links | Reactome: R-HSA-427975 |
| Cellular Localisation | Apical Cell MembraneMulti-Pass Membrane ProteinCytoplasmic VesiclePhagosome MembraneCell MembraneAssociated With The Cell Membrane In Resting Macrophages And Enriched In Phagocytic Cups And Phagosomes After Particle Internalization |
| Alternative Antibody Names | Anti-Solute Carrier Family 15 Member 2 antibodyAnti-Kidney H(+/Peptide Cotransporter antibodyAnti-Oligopeptide Transporter - Kidney Isoform antibodyAnti-Peptide Transporter 2 antibodyAnti-SLC15A2 antibodyAnti-PEPT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
