| Host: | Rabbit |
| Applications: | WB/IHC |
| Reactivity: | Human/Rat/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Paternally-expressed gene 3 protein (1031-1080 aa) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000IHC-P 1:50-300 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PEG3 |
| Gene ID: | 5178 |
| Uniprot ID: | PEG3_HUMAN |
| Immunogen Region: | 1031-1080 aa |
| Specificity: | PEG3 Polyclonal Antibody detects endogenous levels of PEG3 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human PEG3 at the amino acid range 1031-1080 |
| Function | Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Possesses a tumor suppressing activity in glioma cells. |
| Protein Name | Paternally-Expressed Gene 3 ProteinZinc Finger And Scan Domain-Containing Protein 24 |
| Cellular Localisation | NucleusCytoplasm |
| Alternative Antibody Names | Anti-Paternally-Expressed Gene 3 Protein antibodyAnti-Zinc Finger And Scan Domain-Containing Protein 24 antibodyAnti-PEG3 antibodyAnti-KIAA0287 antibodyAnti-ZSCAN24 antibody |
Information sourced from Uniprot.org