Anti-PDGFB precursor antibody (C-Term) (STJ73600)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-PDGFB precursor (C-Term) is suitable for use in ELISA, Immunofluorescence and Flow Cytometry research applications. |
| Applications | Pep-ELISA/IF/FC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Dog/Cow/Sheep |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.IF: Strong expression of the protein seen in the vesicles of MCF7 cells. Recommended concentration: 10µg/ml. FC:Flow cytometric analysis of HeLa cells. Recommended concentration: 10ug/m |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | PDGFB |
| Gene ID | 5155 |
| Uniprot ID | PDGFB_HUMAN |
| Accession Number | NP_002599.1; NP_148937.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | KHRKFKHTHDKT |
| Specificity | This antibody is expected to recognize isoform 1 and 2 (NP_002599.1; NP_148937.1). |
Additional Info
| Function | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA. |
| Protein Name | Platelet-Derived Growth Factor Subunit BPdgf Subunit BPdgf-2Platelet-Derived Growth Factor B ChainPlatelet-Derived Growth Factor Beta PolypeptideProto-Oncogene C-SisBecaplermin |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1257604Reactome: R-HSA-186763Reactome: R-HSA-186797Reactome: R-HSA-2219530Reactome: R-HSA-3000171Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | SecretedReleased By Platelets Upon Wounding |
| Alternative Antibody Names | Anti-Platelet-Derived Growth Factor Subunit B antibodyAnti-Pdgf Subunit B antibodyAnti-Pdgf-2 antibodyAnti-Platelet-Derived Growth Factor B Chain antibodyAnti-Platelet-Derived Growth Factor Beta Polypeptide antibodyAnti-Proto-Oncogene C-Sis antibodyAnti-Becaplermin antibodyAnti-PDGFB antibodyAnti-PDGF2 antibodyAnti-SIS antibody |
Information sourced from Uniprot.org