• WB of PDE7ZA antibody with SKNMBE (1), MCF7 (2), Hu (3) and rat testis (4). Upper panel blotted with Phospho-PDE7A (STJ502624) and lower panel PDE7A (STJ502365).

Anti-PDE7A antibody (STJ502365)

SKU:
STJ502365-100

£481.50
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Host: Rabbit
Applications: CM/ELISA/ICC/IF/IHC/IP/WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE7A is suitable for use in Confocal Microscopy, ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.50-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:250
IHC: 1:100
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE7A
Gene ID: 5150
Uniprot ID: PDE7A_HUMAN
Specificity: This antibody is specific for PDE7A variants and will not cross-react with PDE7B or other PDE family members.
Immunogen: Synthetic cyclic peptide common to all PDE7A variants
Tissue Specificity Isoform PDE7A1: Found at high levels in skeletal muscle and at low levels in a variety of tissues including brain and heart. It is expressed as well in two T-cell lines. Isoform PDE7A2: Found abundantly in skeletal muscle and at low levels in heart.
Function Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May have a role in muscle signal transduction.
Protein Name High Affinity Camp-Specific 3' -5'-Cyclic Phosphodiesterase 7a
Hcp1
Tm22
Database Links Reactome: R-HSA-418555
Cellular Localisation Isoform Pde7a1: Cytoplasm
Cytosol
Pde7a1 (57 Kda) Is Located Mostly To Soluble Cellular Fractions
Isoform Pde7a2: Cytoplasm
Pde7a2 (50 Kda) Is Located To Particulate Cellular Fractions
Alternative Antibody Names Anti-High Affinity Camp-Specific 3' -5'-Cyclic Phosphodiesterase 7a antibody
Anti-Hcp1 antibody
Anti-Tm22 antibody
Anti-PDE7A antibody

Information sourced from Uniprot.org

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