| Host: | Rabbit |
| Applications: | CM/ELISA/FRET/ICC/IF/IHC/IP/WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-PDE2A (C-Term) is suitable for use in Confocal Microscopy, ELISA, FRET, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation and Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide). |
| Purification: | Affinity Purified |
| Concentration: | 0.7 µg/µl |
| Dilution Range: | WB: 1:250-1:1, 000DB: 1:10, 000ELISA: 1:10, 000IP: 1:200IHC: 1:250-1:1, 000ICC: 1:250-1:1, 000IF: 1:150-1:1, 000CFM: 1:250-1:1, 000 |
| Storage Instruction: | Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Immunogen Region: | C-Term |
| Specificity: | This antibody will label PDE2A1, PDE2A2, PDE2A3 and PDE2A4 variants. |
| Immunogen: | Synthetic peptide corresponding to unique C-terminal amino acid sequence on PDE2A gene. |
| Background | Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis. |
Information sourced from Uniprot.org
