Anti-PDE10A antibody (50-120) {Biotin} (STJ502203)

SKU:
STJ502203-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PDE10A (50-120) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Biotin
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.67-0.75 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PDE10A
Gene ID: 10846
Uniprot ID: PDE10_HUMAN
Immunogen Region: 50-120
Immunogen: Synthetic peptide taken within amino acid region 50-120 on PDE10A12 protein.
Post Translational Modifications Isoform PDE10A2: Phosphorylated on Thr-16.
Function Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. Can hydrolyze both cAMP and cGMP, but has higher affinity for cAMP and is more efficient with cAMP as substrate. May play a critical role in regulating cAMP and cGMP levels in the striatum, a region of the brain that contributes to the control of movement and cognition.
Protein Name Camp And Camp-Inhibited Cgmp 3' -5'-Cyclic Phosphodiesterase 10a
Database Links Reactome: R-HSA-418457
Reactome: R-HSA-418555
Cellular Localisation Cytoplasm
Cytosol
Alternative Antibody Names Anti-Camp And Camp-Inhibited Cgmp 3' -5'-Cyclic Phosphodiesterase 10a antibody
Anti-PDE10A antibody

Information sourced from Uniprot.org

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