Anti-PAXBP1 antibody (STJ190829)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-PAX3-and PAX7-binding protein 1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAXBP1 |
| Gene ID | 94104 |
| Uniprot ID | PAXB1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | GCFC1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Adapter protein linking the transcription factors PAX3 and PAX7 to the histone methylation machinery and involved in myogenesis. Associates with a histone methyltransferase complex that specifically mediates dimethylation and trimethylation of 'Lys-4' of histone H3. Mediates the recruitment of that complex to the transcription factors PAX3 and PAX7 on chromatin to regulate the expression of genes involved in muscle progenitor cells proliferation including ID3 and CDC20. |
| Protein Name | Pax3- And Pax7-Binding Protein 1Gc-Rich Sequence Dna-Binding Factor 1 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Pax3- And Pax7-Binding Protein 1 antibodyAnti-Gc-Rich Sequence Dna-Binding Factor 1 antibodyAnti-PAXBP1 antibodyAnti-C21orf66 antibodyAnti-GCFC antibodyAnti-GCFC1 antibody |
Information sourced from Uniprot.org