| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | PAX8 |
| Gene ID: | 7849 |
| Uniprot ID: | PAX8_HUMAN |
| Immunogen Region: | 200-300 |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human PAX8 (NP_003457.1). |
| Immunogen Sequence: | DSDQDSCRLSIDSQSSSSGP RKHLRTDAFSQHHLEPLECP FERQHYPEAYASPSHTKGEQ GLYPLPLLNSTLDDGKATLT PSNTPLGRNLSTHQTYPVVA D |
| Tissue Specificity | Expressed in the excretory system, thyroid gland and Wilms tumors. |
| Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
| Protein Name | Paired Box Protein Pax-8 |
| Database Links | Reactome: R-HSA-9761174Reactome: R-HSA-9830364 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-8 antibodyAnti-PAX8 antibody |
Information sourced from Uniprot.org