• Western blot analysis of lysate from 293 cells, using PAX5 Antibody.
  • Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded mouse-spleen, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
  • Immunohistochemical analysis of paraffin-embedded human-tonsil, antibody was diluted at 1:100
  • Western blot analysis of 293 cells using Pax-5 Polyclonal Antibody.. Secondary antibody was diluted at 1:20000 cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003, Inventbiotech, MN, USA).

Anti-PAX5 antibody (171-220 aa) (STJ96677)

SKU:
STJ96677

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: WB/IHC/IF/ELISA
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Paired box protein Pax-5 (171-220 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
IHC-P 1:100-1:300
ELISA 1:20000
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: PAX5
Gene ID: 5079
Uniprot ID: PAX5_HUMAN
Immunogen Region: 171-220 aa
Specificity: Pax-5 Polyclonal Antibody detects endogenous levels of Pax-5 protein.
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PAX5 at the amino acid range 171-220
Function Transcription factor that plays an essential role in commitment of lymphoid progenitors to the B-lymphocyte lineage. Fulfills a dual role by repressing B-lineage inappropriate genes and simultaneously activating B-lineage-specific genes. In turn, regulates cell adhesion and migration, induces V(H)-to-D(H)J(H) recombination, facilitates pre-B-cell receptor signaling and promotes development to the mature B-cell stage. Repression of the cohesin-release factor WAPL causes global changes of the chromosomal architecture in pro-B cells to facilitate the generation of a diverse antibody repertoire. (Microbial infection) Plays an essential role in the maintenance of Epstein-Barr virus genome copy number within the host cell by promoting EBNA1/oriP-dependent binding and transcription. Participates also in the inhibition of lytic EBV reactivation by modulating viral BZLF1 activity.
Protein Name Paired Box Protein Pax-5
B-Cell-Specific Transcription Factor
Bsap
Database Links Reactome: R-HSA-8939245
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Paired Box Protein Pax-5 antibody
Anti-B-Cell-Specific Transcription Factor antibody
Anti-Bsap antibody
Anti-PAX5 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance