Anti-PAX4 antibody (250-300) (STJ502152)

SKU:
STJ502152-100

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Host: Rabbit
Applications: ELISA/WB
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-PAX4 (250-300) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Purification: Affinity Purified
Concentration: 0.92-1.25 µg/µl
Dilution Range: WB: 1:500
DB: 1:10, 000
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: PAX4Uniprot ID=PAX4_HUMAN"
Immunogen Region: 250-300
Immunogen: Synthetic peptide taken within amino acid region 250-300, corresponding to unique amino acid sequence on PAX4 protein.
Function Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Protein Name Paired Box Protein Pax-4
Cellular Localisation Nucleus
Alternative Antibody Names Anti-Paired Box Protein Pax-4 antibody
Anti-PAX4 antibody

Information sourced from Uniprot.org

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