| Host: | Mouse |
| Applications: | IHC-P |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Mouse monoclonal antibody anti-PAX-8 is suitable for use in Immunohistochemistry research applications. |
| Clonality : | Monoclonal |
| Clone ID : | ZM28 |
| Conjugation: | Unconjugated |
| Isotype: | IgG2b/Kappa |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | PAX8 |
| Gene ID: | 7849 |
| Uniprot ID: | PAX8_HUMAN |
| Specificity: | Positive control: Ovarian serous carcinoma |
| Immunogen: | Recombinant human PAX-8 protein |
| Tissue Specificity | Expressed in the excretory system, thyroid gland and Wilms tumors. |
| Function | Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells. |
| Protein Name | Paired Box Protein Pax-8 |
| Database Links | Reactome: R-HSA-9761174Reactome: R-HSA-9830364 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Paired Box Protein Pax-8 antibodyAnti-PAX8 antibody |
Information sourced from Uniprot.org