| Short Description : | Mouse monoclonal Parathyroid hormone (1-34aa) antibody for use in IHC-P in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC-P |
| Host: | Mouse |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | ZM207 |
| Isotype: | IgG2bk |
| Conjugation: | Unconjugated |
| Purification: | Affinity purified |
| Dilution Range: | 1:100‐200 |
| Formulation: | Tris-HCI buffer containing stabilizing protein (BSA) and <0.1% ProClin |
| Storage Instruction: | Store at 2‐8°C for up to 24 months. Predilute: Ready to use, no reconstitution necessary. Concentrate: Use dilution range and appropriate lab‐standardized diluent. Stability after dilution: 7 days at 24°C, 3 months at 2‐8°C, 6months at ‐20°C. |
| Gene Symbol: | PTH |
| Gene ID: | 5741 |
| Uniprot ID: | PTHY_HUMAN |
| Immunogen: | A synthetic peptide around aa 1-34 of human mature-PTH-polypeptide; A recombinant fragment around aa 32-115 of human mature PTH-polypeptide (exact sequence is proprietary) |
| Immunogen Region: | 1-34aa |
| Specificity: | Positive control: Parathyroid |
| Function | Parathyroid hormone elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Acts by binding to its receptor, PTH1R, activating G protein-coupled receptor signaling. Stimulates 1-14C-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells. |
| Protein Name | Parathyroid HormonePthParathormoneParathyrin |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Parathyroid Hormone antibodyAnti-Pth antibodyAnti-Parathormone antibodyAnti-Parathyrin antibodyAnti-PTH antibody |
Information sourced from Uniprot.org
