| Host: |
Rabbit |
| Applications: |
ELISA/IP/WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-PAR1 (390-440) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Biotin |
| Isotype: |
IgG |
| Purification: |
Affinity Purified |
| Concentration: |
0.63-0.65 µg/µl |
| Dilution Range: |
WB: 1:250DB: 1:10, 000ELISA: 1:10, 000IP: 1:200 |
| Storage Instruction: |
Store at-20°C for long term storage. Avoid freeze-thaw cycles. |
| Gene Symbol: |
F2r |
| Gene ID: |
14062 |
| Uniprot ID: |
PAR1_MOUSE |
| Immunogen Region: |
390-440 |
| Immunogen: |
Synthetic peptide taken within amino acid region 390-440 on mouse PAR1 protein. |
| Post Translational Modifications | Proteolytic cleavage by thrombin generates a new N-terminus that functions as a tethered ligand. Also proteolytically cleaved by cathepsin CTSG. Phosphorylated in the C-terminal tail.probably mediating desensitization prior to the uncoupling and internalization of the receptor. |
| Function | High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. |
| Protein Name | Proteinase-Activated Receptor 1Par-1Thrombin Receptor |
| Database Links | Reactome: R-MMU-140875Reactome: -MMU-375276Reactome: -MMU-416476Reactome: -MMU-456926 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Proteinase-Activated Receptor 1 antibodyAnti-Par-1 antibodyAnti-Thrombin Receptor antibodyAnti-F2r antibodyAnti-Cf2r antibodyAnti-Par1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
