Anti-PAPSS1 antibody (STJA0007733)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human PAPSS1
General Information
| Short Description | Rabbit polyclonal anti-Bifunctional 3 phosphoadenosine 5 phosphosulfate synthase 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PAPSS1 |
| Gene ID | 9061 |
| Uniprot ID | PAPS1_HUMAN |
| Immunogen | Synthesized peptide derived from human PAPSS1 |
| Specificity | This antibody detects endogenous levels of PAPSS1 at Human, Mouse |
Additional Info
| Function | Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate.APS appears to be only an intermediate in the sulfate-activation pathway. Required for normal biosynthesis of sulfated L-selectin ligands in endothelial cells. |
| Protein Name | Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1Paps Synthase 1Papss 1Sulfurylase Kinase 1Sk 1Sk1 Includes - Sulfate AdenylyltransferaseAtp-SulfurylaseSulfate Adenylate TransferaseSat - Adenylyl-Sulfate Kinase3'-Phosphoadenosine-5'-Phosphosulfate SynthaseAps KinaseAdenosine-5'-Phosphosulfate 3'-PhosphotransferaseAdenylylsulfate 3'-Phosphotransferase |
| Database Links | Reactome: R-HSA-174362Reactome: R-HSA-2408550Reactome: R-HSA-6802952 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Bifunctional 3'-Phosphoadenosine 5'-Phosphosulfate Synthase 1 antibodyAnti-Paps Synthase 1 antibodyAnti-Papss 1 antibodyAnti-Sulfurylase Kinase 1 antibodyAnti-Sk 1 antibodyAnti-Sk1 Includes - Sulfate Adenylyltransferase antibodyAnti-Atp-Sulfurylase antibodyAnti-Sulfate Adenylate Transferase antibodyAnti-Sat - Adenylyl-Sulfate Kinase antibodyAnti-3'-Phosphoadenosine-5'-Phosphosulfate Synthase antibodyAnti-Aps Kinase antibodyAnti-Adenosine-5'-Phosphosulfate 3'-Phosphotransferase antibodyAnti-Adenylylsulfate 3'-Phosphotransferase antibodyAnti-PAPSS1 antibodyAnti-ATPSK1 antibodyAnti-PAPSS antibody |
Information sourced from Uniprot.org